منابع مشابه
Lactic Acidosis
Lactic acidosis is a form of metabolic acidosis due to the inadequate clearance of lactic acid from the blood. Lactate is a byproduct of anaerobic respiration and is normally cleared from the blood by the liver, kidney and skeletal muscle. Lactic acidosis occurs when the body's buffering systems are overloaded and tends to cause a pH of ≤7.25 with plasma lactate ≥5 mmol/L. It is usually caused ...
متن کاملLactic acidosis.
A 33-year-old male was admitted to Michael Reese Hospital and Medical Center for evaluation of weight loss, dyspnea, and fever. He had factor Vill-deficient hemophilia and had been chronically ill over several months with a cough productive of scanty sputum, weight loss of 15 Ibs, low-grade fever, and progressive dyspnea on exertion. The medical history was notable for right total hip replaceme...
متن کاملLactic Acidosis
by exchanige transfusioin. Muscle activity is associate(l with a higher blood lactate concenltrationi thani is observed in iron-replete aniimals. The accumulation of lactate is a result of excessive productioni as lactate clearancie fromn the 1)loo0( was shown to be unaffecte(l. By acljusting the work loa(l to a lower level, it was possible to (livide iron-deficient animilals into two groups, o...
متن کاملMetformin and Lactic Acidosis
Probably the most common mechanism by which metformin elevates blood lactate is by inducing catecholamine release in those who regulate or prescribe it. Caution in restricting the use of metformin for the treatment of type 2 diabetes has been rationalized on the basis of J) its chemical identity as a biguanide, 2) its ability to modify hepatic intermediary metabolism, 3) its administration to i...
متن کاملStatin precipitated lactic acidosis?
An 82 year old woman was admitted with worsening dyspnoea. Arterial blood gases were taken on air and revealed a pH of 7.39, with a partial pressure of CO2 (pCO2) of 1.2 kPa, pO2 of 19.3 kPa, HCO3 of 13.8 mmol/litre, and base excess of -16.3 mmol/litre: a compensated metabolic acidosis with hyperventilation induced hypocapnia, which is known to be a feature of lactic acidosis. There was also an...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Kidney International
سال: 1986
ISSN: 0085-2538
DOI: 10.1038/ki.1986.62